Scientific Publications

PhenoGuard Protein Discovery Engine

1. Panchision D., Martin-DeLeon P, Takeshima T, Johnston J, Shimoda K, Tsoulfas P, McKay R, Commissiong JW (1998). An immortalized Type-1 Astrocyte Origin of a Dopaminergic Neurotrophic Factor. J Mol Neurosci. 11-208-221
2. Takeshima T., Shimoda K. Johnston J.M., Commissiong J. (1996). Standard methods to bioassay neurotrophic factors for dopaminergic neurons. J Neurosci Meth 67: 27-41
3. Voutilainen M, Back S, Porsti E., Toppinen L, Lindgren L, Lindholm P, Peranen J, Saarma M and Tuominen R (2009). Mesencephalic Astrocyte-derived Neurotrophic Factor is Neurorestorative in a Rat Model of Parkinson’s Disease. J Neurosci, July 29, 2009. 29(30):9651–9659.

AMRS001

1. Yong-Qiang Yu1, Lian-Cheng Liu1, Fa-Cai Wang2, Yan Liang2, Da-Qin Cha2, Jing-Jing Zhang2, Yu-Jun Shen2, Hai-Ping Wang2, Shengyun Fang2,3 and Yu-Xian Shen2 (2009). Induction profile of MANF/ARMET by cerebral ischemia and its implication for neuron protection, J CBFM Sept 23: 1–13
2. Airavaara M, Shen H, Kuo C-C, Peränen J, Saarma M, Hoffer B, Wang Y (2009) Mesencephalic astrocyte-derived neurotrophic factor reduces ischemic brain injury and promotes behavioral recovery in rats. J Comp Neurol 515: 116-124.
3. Parkash V, Lindholm P, Peranen J, Kalkkinen N, Oksanen E, Saarma M, Leppanen VM, Goldman A (2009). The structure of the conserved neurotrophic factors MANF and CDNF explains why they are bifunctional. Protein Engineering Design Selection 22: 233-24.
4. Palgia M, Lindstrom R, Peranen J, T. Piepponen P, Saarma M, Tapio I. Heino TI (2009) Evidence that DmMANF is an invertebrate neurotrophic factor supporting dopaminergic neurons. PNAS 106: 2429–2434.
5. Tadimalla A, Belmont PJ, Thuerauf DJ, Glassy MS, Martindale JJ, Gude N, Sussman MA, Glembotski CC (2008) Mesencephalic Astrocyte-Derived Neurotrophic Factor Is an Ischemia-Inducible Secreted Endoplasmic Reticulum Stress Response Protein in the Heart. Cir Res 103: 1249-1258.
6. Lindholm P, Andressoo J-O, Kalkkinen N, Kokaia Z, Lindvall O, Timmusk T, Peranen J, Saarma M (2008). MANF is widely expressed in mammalian tissues and differently regulated after ischemic and epileptic insults in rodent brain. Mol Cell Neurosci 39: 356-371
7. Apostolou A, Shen Y, Liang Y, Lou Y, Fang S. (2008) Armet, a UPR-upregulated protein, inhibits cell proliferation and ER stress-induced cell death. Exp Cell Res 14: 2454-2467.
8. Mizobuchi N, Hoseki J, Kubota H, Toyokuni Y, Nozaki K, Naitoh M, Koizumi A, Nagata K. (2007) ARMET is a Soluble ER Protein Induced by the Unfolded Protein Response via ERSE-II Element. Cell Struct Funct 32: 41-50.
9. Zhou C, Xiao C, Commissiong JW, Krnjevic K, Ye JH. (2006) Mesencephalic astrocyte-derived neurotrophic factor enhances nigral [gamma]-aminobutyric acid release. NeuroReport 17: 293-297.
10. Petrova PS, Raibekas A, Pevsner J, Vigo N, Anafi M, Moore MK, Peaire A, Shridhar V, Smith DI, Kelly J, Durocher Y, Commissiong JW. (2004) Discovering novel phenotype-selective neurotrophic factors to treat neurodegenerative diseases. Prog Brain Res 146: 168-183.
11. Petrova PS, Raibekas A, Pevsner J, Vigo N, Anafi M, Moore MK, Peaire AE, Shridhar V, Smith DI, Kelly J, Durocher Y, Commissiong JW. (2003) MANF: a new mesencephalic, astrocyte-derived neurotrophic factor with selectivity for dopaminergic neurons. J Mol Neurosci 20: 173-188.